Commentary: Time for a re-assessment of the incidence of intentional and unintentional injury in India and South East Asia

Eddleston, Michael, and Flemming Konradsen. “Commentary: Time for a re-assessment of the incidence of intentional and unintentional injury in India and South East Asia.” International journal of epidemiology 36, no. 1 (2007): 208-211. summary: In this issue of International Journal of Epidemiology, Gajalakshmi and Peto publish their results from a community study of deaths from … Continue Reading »

Organophosphates: New Antidotes from Old Drugs

Andrew, Dawson. “Organophosphates: New Antidotes from Old Drugs.” Journal of the Indian Society of Toxicology 2, no. 1 (2006). abstract:  Asia carries a disproportionate burden of illness from acute and chronic toxicity. Organophosphate pesticides contribute substantially to the burden of illness. For many years this class of pesticides had been treated as a relatively homogenous … Continue Reading »

How the level of resources and hospital staff attitude in primary care hospitals in rural Sri Lanka affect poisoning patient outcome

Senarathna, D. L. P. “How the level of resources and hospital staff attitude in primary care hospitals in rural Sri Lanka affect poisoning patient outcome.”Centre for Clinical Epidemiology and Biostatistics. Newcastle, Australia: University of Newcastle (2006): 1-89. summary:  Background: Deliberately self poisoning with poisonous substances like agrochemicals has become an epidemic in rural parts of … Continue Reading »

Pralidoxime for organophosphate poisoning

Eyer, Peter, and Nicholas Buckley. “Pralidoxime for organophosphate poisoning.” The Lancet 368, no. 9553 (2006): 2110-2111. summary:  From their randomised trial, Kirti Pawar and colleagues report in today’s Lancet on two pralidoxime-dosing schemes in 200 patients who had moderately severe self-poisoning with organophosphorus insecticide.1 After a 2-g loading dose over 30 min, half received a … Continue Reading »

Why suicide rates are high in China

Eddleston, Michael, and David Gunnell. “Why suicide rates are high in China.”Science (New York, NY) 311, no. 5768 (2006): 1711. Sir, We read with interest Miller’s article describing a discrepancy between Chinese rates of suicide and depression (27th January 2006). However, we feel that Miller, by concentrating on fatal self-harm rather thanall acts of self-harm, … Continue Reading »

Deaths from pesticide poisoning: a global response

Bertolote, José Manoe, Alexandra Fleischmann, Michael Eddleston, and D. Gunnell. “Deaths from pesticide poisoning: a global response.” The British Journal of Psychiatry 189, no. 3 (2006): 201-203. abstract: Self-poisoning with pesticides accounts for about a third of all suicides worldwide. To tackle this problem, the World Health Organization announced a global public health initiative in … Continue Reading »

Antidotes for acute cardenolide (cardiac glycoside) poisoning

Roberts, Darren M., and Nick Buckley. “Antidotes for acute cardenolide (cardiac glycoside) poisoning.” The Cochrane Library (2006). Background Cardenolides are naturally occurring plant toxins which act primarily on the heart. While poisoning with the digitalis cardenolides (digoxin and digitoxin) are reported worldwide, cardiotoxicity from other cardenolides such as the yellow oleander are also a major … Continue Reading »

Gastric Lavage in Acute Organophosphorus Pesticide poisoning (GLAOP) – a randomised controlled trial of multiple vs. single gastric lavage in unselected acute organophosphorus pesticide poisoning

Li, Yi, XueZhong Yu, Zhong Wang, HouLi Wang, XiangHuai Zhao, YuPing Cao, WeiZhan Wang, and Michael Eddleston. “Gastric Lavage in Acute Organophosphorus Pesticide poisoning (GLAOP)–a randomised controlled trial of multiple vs. single gastric lavage in unselected acute organophosphorus pesticide poisoning.” BMC emergency medicine 6, no. 1 (2006): 10. abstract:  Background Organophosphorus (OP) pesticide poisoning is … Continue Reading »

Physical vulnerability and fatal self-harm in the elderly

Eddleston, Michael, Mathisha Dissanayake, MH Rezvi Sheriff, David A. Warrell, and David Gunnell. “Physical vulnerability and fatal self-harm in the elderly.” The British Journal of Psychiatry 189, no. 3 (2006): 278-279. abstract:  Although the high rate of suicide in elderly people is conventionally explained as being due to greater intent to die, we have noted … Continue Reading »

Pharmacokinetics of digoxin cross-reacting substances in patients with acute yellow oleander (Thevetia peruviana) poisoning, including the effect of activated charcoal.

Roberts, Darren M., Emma Southcott, Julia M. Potter, Michael S. Roberts, Michael Eddleston, and Nick A. Buckley. “Pharmacokinetics of digoxin cross-reacting substances in patients with acute yellow Oleander (Thevetia peruviana) poisoning, including the effect of activated charcoal.” Therapeutic drug monitoring 28, no. 6 (2006): 784. abstract: Intentional self-poisonings with seeds from the yellow oleander tree … Continue Reading »