Publications

The clinical toxicity of Imidacloprid self-poisoning following the introduction of newer formulations

Varan Perananthan, Fahim Mohamed, Seyed Shahmy, Indika Gawarammana, Andrew Dawson, Nicholas Buckley Objective: Self-poisoning with Imidacloprid has been previously shown to have low toxicity in humans. Since 2007 newer formulations of Imidacloprid with unknown solvents have been introduced. Kohinoor Imidacloprid (2007), Provado Imidacloprid (2007) ...

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Association between co-ingested alcohol and deliberate self-poisonings

Jeevan Dhanarisi, Indika Gawarammana, Seyed Shahmy, Vindya Pathiraja, Fahim Mohamed, Michael Eddleston Objective: Sri Lanka has one of the highest alcohol consumption rates in the world. Acute use of alcohol is a potent risk factor for deliberate self-harm, though the nature of this risk is poorly understood. The aim of this study was to compare .....

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Pilot study assessing gut toxicity in acute self-poisoning using a novel biomarker Intestinal Fatty Acid Binding Protein

Varan Perananthan, Thilini Wijerathna, Fahim Mohamed, Indika Gawarammana, Andrew Dawson, Nicholas Buckley Objective: Gut toxicity or reactive gastropathy is expected following oral ingestion of various toxins. However, the extent of enterocyte damage has not been previously quantified. Intestinal Fatty Acid Binding Protein (I-FABP) is a cystolic pr...

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Medicinal overdoses in Sri Lanka: Associated factors – a qualitative study

Lakmini De Silva, Andrew Dawson, Sampath Tennakoon, Indika Gawarammana, Thilini Rajapakse Objective: Attempted or non-fatal self-poisoning is a major public health problem in Sri Lanka. The objective of this study was to explore the factors associated with the self-poisoning behavior of those who have ingested a medicinal overdose. Methods: This wa...

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Gut toxicity in Russell’s and hump-nosed Viper envenomation

Varan Perananthan, Thilini Wijerathne, Fahim Mohamed, Indika Gawarammana, Andrew Dawson, Nicholas Buckley Objective: Abdominal pain is known to be an early clinical predictor of severe systemic Russell’s Viper (RV) envenomation and is often associated with the later development of coagulopathy and neurotoxicity. The mechanism of abdominal pain st...

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