Performance of the 20-minute whole blood clotting test in detecting venom induced consumption coagulopathy from Russell’s viper (Daboia russelii) bites.

I. Ratnayake (1), F. Shihana (1), D. M. Dissanayake (1, 2), N. A. Buckley (1, 3), K. Maduwage (4, 5), G. K. Isbister (1, 4) (1) South Asian Clinical Toxicology Research Collaboration (SACTRC), Faculty of Medicine, University of Peradeniya, Peradeniya, Sri Lanka; (2) Department of Pathology, Faculty of Medicine, University of Peradeniya, Peradeniya, Sri Lanka; … Continue Reading »

Utilization of boxes for pesticide storage in Sri Lanka

Pieris, R., Weerasinghe, M., Abeywickrama, T., Manuweera, G., Eddleston, M., Dawson, A., Konradsen, F. and Edinburgh, U.K., Utilization of boxes for pesticide storage in Sri Lanka. Abstract Pesticide self-poisoning is now considered one of the two most common methods of suicide worldwide. Encouraging safe storage of pesticides is one particular approach aimed at reducing pesticide … Continue Reading »

A randomized controlled trial of fresh frozen plasma for coagulopathy in Russell’s viper (Daboia russelii) envenoming

Isbister, G.K., Jayamanne, S., Mohamed, F., Dawson, A.H., Maduwage, K., Gawarammana, I., Lalloo, D.G., Silva, H.J., Scorgie, F.E., Lincz, L.F. and Buckley, N.A., 2017. A randomized controlled trial of fresh frozen plasma for coagulopathy in Russell’s viper (Daboia russelii) envenoming. Journal of Thrombosis and Haemostasis. Abstract Background: Russell’s viper (Daboia russelii) envenoming is a major … Continue Reading »

Acceptance and attitudes of healthcare staff towards the introduction of clinical pharmacy service: a descriptive cross-sectional study from a tertiary care hospital in Sri Lanka.

Shanika, L.G.T., Wijekoon, C.N., Jayamanne, S., Coombes, J., Coombes, I., Mamunuwa, N., Dawson, A.H. and De Silva, H.A., 2017. Acceptance and attitudes of healthcare staff towards the introduction of clinical pharmacy service: a descriptive cross-sectional study from a tertiary care hospital in Sri Lanka. BMC Health Services Research, 17(1), p.46. Abstract BACKGROUND: Multidisciplinary patient management … Continue Reading »

Impact of paraquat regulation on suicide in South Korea.

Cha, E.S., Chang, S.S., Gunnell, D., Eddleston, M., Khang, Y.H. and Lee, W.J., 2016. Impact of paraquat regulation on suicide in South Korea. International journal of epidemiology, 45(2), pp.470-479. Abstract BACKGROUND: Ingestion of pesticides (mainly paraquat) accounted for one-fifth of suicides in South Korea in 2006-10. We investigated the effect on suicide mortality of regulatory … Continue Reading »

Development of a Snakebite risk map for Sri Lanka

Ediriweera, D.S., Kasturiratne, A., Pathmeswaran, A., Kithsiri, N., Gunawardena, B.A.W., Jayamanne, S.F., Kennedy, G., Isbister, A.D., Giorgi, E., Diggle, P.J. and Lalloo, D.G., Development of a Snakebite risk map for Sri Lanka. Introduction Snakebite is a neglected tropical disease Snakebite causes significant morbidity and mortality in poor rural communities Sri Lanka has 92 snake species … Continue Reading »

Development of a new polyspecific antivenom for snakebite envenoming in Sri Lanka: Analysis of its preclinical efficacy as compared to a currently available antivenom.

Villalta, M., Sánchez, A., Herrera, M., Vargas, M., Segura, Á., Cerdas, M., Estrada, R., Gawarammana, I., Keyler, D.E., McWhorter, K. and Malleappah, R., 2016. Development of a new polyspecific antivenom for snakebite envenoming in Sri Lanka: Analysis of its preclinical efficacy as compared to a currently available antivenom. Toxicon. Abstract A new whole IgG, freeze-dried, … Continue Reading »

Arterial stiffness & Sri Lankan chronic kidney disease of unknown origin

Gifford, F., Kimmitt, R., Herath, C., Webb, D.J., Melville, V., Siribaddana, S., Eddleston, M. and Dhaun, N., 2016. Arterial stiffness & Sri Lankan chronic kidney disease of unknown origin.Scientific Reports, 6, p.32599. Abstract Chronic kidney disease (CKD) is common and independently associated with cardiovascular disease (CVD). Arterial stiffness contributes to CVD risk in CKD. In … Continue Reading »

Methemoglobin measurements are underestimated by the Radical 7 co-oximeter: experience from a series of moderate to severe propanil poisonings

Elspeth Hulse, Fathima Shihana, Nicholas A Buckley Abstract Introduction: In Asia methemoglobinemia (MetHb) is commonly caused through self-poisoning with the pesticide propranil. MetHb can cause hypoxia, coma and death, but usually responds to methylene blue. It is therefore vital to have accurate methods to measure blood MetHb to guide appropriate treatments. The gold standard to … Continue Reading »

A bedside test for methemoglobinemia, Sri Lanka

Shihana, F., Dawson, A.H. and Buckley, N.A., 2016. A bedside test for methemoglobinemia, Sri Lanka. Bulletin of the World Health Organization,94(8), p.622. Abstract Problem  Propanil is an aniline herbicide that is widely used for rice cultivation, but is also used for self-poisoning. Toxicity from propanil is largely due to methemoglobinemia. In resource-poor settings, the capacity to … Continue Reading »